DIDIER MESEURE

Doctor

Hôpital - Paris

Spécialités / domaines

Biopathologie

Functions within Institut Curie:

Practitioner

PMDT - Pathologie

Présentation

Doctor Didier Meseure is a pathologist and specialist in Cancer control Centres since 2005. He hosts the PATHEX Experimental Pathology unit, a platform of tissue expertise designed to carry out the histological component of the cognitive and pre-clinical research projects of the institutional teams belonging to the Centre of Research of the Curie Institute and the Industrial partners.

This platform develops and offers innovative in situ techniques (microdissection, immuno-Fish, immunoligation, RNA-fish/ichs and immunohistochemistry multiplexed sequential). The platform's expertise covers various scientific fields including immuno-oncology, epigenetics and non-coding ARNs, cell signalling pathways, microenvironments and stem cells. Since 2013, the platform has participated in the realization of 351 projects and the publication of 52 articles, journals and book chapters.

Actualites

Mouse colon characterized in green fluorescence by the proliferative cells generated by stem cells that re-new the epithelial tissue every 5 days, the quantity of which depends on mechanical control parameters: 1/ natural pulsations of the colon in healthy physiological configuration, 2/ tumor growth pressure causing them to increase in the pathological tumor configuration, amplifying the hyperproliferation and tumor growth process via mechanical pathway.

@Florence Broders / Emmanuel Farge

Cancer under pressure