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GENEVIEVE ALMOUZNI

Doctor,
Research Director CNRS
Recherche - Paris
Spécialités / domaines
Development, cancer, genetics and epigenetics
Functions within Institut Curie:
Présentation

Geneviève ALMOUZNI, PhD (EMBO member, Member of the French Academy of Sciences, fellow of the American Association for the Advancement of Sciences, Director of the Research Center of the Institut Curie from sept 2013 to September 2018 and honorary director since then) is director of research exceptional class at the CNRS. She is Principal Investigator of the Chromatin dynamics team in the Nuclear Dynamics research Unit (UMR3664 CNRS/Institut Curie) since 1999. She is a world leader in understanding genome organization and function during development and disease in particular in cancer. She has combined biochemistry, cell biology and physical approaches with advanced imaging to explore chromatin dynamics. Overall, G. Almouzni authored more than 220 publications and deposited 5 patents. Active in the field of Epigenetics and European actions, she coordinated the EpiGeneSys Network of Excellence to move epigenetics towards systems biology. She is highly engaged in promoting young scientist career. She received prestigious grants (ERC Advanced Grants) and awards including Woman in Sciences FEBS / EMBO (2013) and the grand prix FRM (2014). She served on the EMBO Council (Vice-chair in 2014), chair of the alliance EU-LIFE, she co-chairs the European initiative LifeTime with Prof. N. Rajewski at the MDC Berlin.

Publications
Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe
eLife
Fouad Ouasti, Maxime Audin, Karine Freon, Jean-Pierre Quivy, Mehdi Tachekort, Elizabeth Cesard, Aurelien Thureau, Virginie Ropars, Paloma F. Varela, Gwenaelle Moal, Ibrahim Soumana-Amadou, Aleksandra Uryga, Pierre Legrand, Jessica Andreani, Raphael Guerois, Genevieve Almouzni, sarah AE lambert, Francoise Ochsenbein
CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas
Nature Communications
Leticia Laura Niborski, Paul Gueguen, Mengliang Ye, Allan Thiolat, Rodrigo Nalio Ramos, Pamela Caudana, Jordan Denizeau, Ludovic Colombeau, Raphaël Rodriguez, Christel Goudot, Jean-Michel Luccarini, Anne Soudé, Bruno Bournique, Pierre Broqua, Luigia Pace, Sylvain Baulande, Christine Sedlik, Jean-Pierre Quivy, Geneviève Almouzni, José L. Cohen, Elina Zueva, Joshua J. Waterfall, Sebastian Amigorena, Eliane Piaggio
CENP-A Regulation and Cancer
Frontiers in Cell and Developmental Biology
Charlène Renaud-Pageot, Jean-Pierre Quivy, Marina Lochhead, Geneviève Almouzni