
MARC-HENRI STERN
Doctor,
Directeur de recherche
Recherche - Paris
Spécialités / domaines
Bioinformatics,
Integrative tumor biology, immunology and environment,
Cancer,
Gynécologie,
Genomics,
Genetics,
Ophtalmologie
Functions within Institut Curie:
- PractitionerPMDT - Génétique
Présentation
Marc-Henri Stern received his doctorate in medicine and his PhD in Sciences (immunology) from the universities of Paris. After his postdoctoral training at N.C.I. (USA), he began his research team at Saint Louis Hospital, Paris, on leukemogenesis and DNA repair defects.
He joined the Curie Institute in 2000, setting up his team in the Inserm unit U830 unit led by Dr. Olivier Delattre, maintaining a medical activity within the Oncogenetics unit led by Prof. Dominique Stoppa-Lyonnet. His team is dedicated to unravel the genetic factors of tumor predisposition and of oncogenesis in adult tumors, including breast and ovarian carcinomas and uveal melanoma, ranging from fundamental and translational research to diagnosis.
Publications
Rare germline heterozygous missense variants in BRCA1-associated protein 1, BAP1, cause a syndromic neurodevelopmental disorder
The American Journal of Human Genetics
Ultraviolet radiation drives mutations in a subset of mucosal melanomas
Nature Communications
A DNA methylation-based liquid biopsy for triple-negative breast cancer
npj Precision Oncology
Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas
JNCI: Journal of the National Cancer Institute
Germline MBD4 Mutations and Predisposition to Uveal Melanoma
JNCI: Journal of the National Cancer Institute
Uveal melanoma
Nature Reviews Disease Primers