Recherches "plusieurs pathologies" CIRCA-HPV (IC 2017-01) Circulating Tumor DNA for the Early Detection of HPV-positive Pelvic Cancer Relapses. Paris, Saint-Cloud BRUNO BUECHER
VADS MK3475-689 (Keynote-689) A Phase III, Randomized, Open-label Study to Evaluate Pembrolizumab as Neoadjuvant Therapy and in Combination With Standard of Care as Adjuvant Therapy for Stage III-IVA Resectable Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA HNSCC). Paris CHRISTOPHE LE TOURNEAU
Pédiatrie Tumeurs solides GO40871 A PHASE I/II, MULTICENTER, OPEN-LABEL, MULTI-ARM;STUDY EVALUATING THE SAFETY, TOLERABILITY,;PHARMACOKINETICS, AND PRELIMINARY ACTIVITY OF;IDASANUTLIN IN COMBINATION WITH EITHER;CHEMOTHERAPY OR VENETOCLAX IN THE TREATMENT OF;PEDIATRIC AND YOUNG ADULT PATIENTS WITH;RELAPSED/REFRACTORY ACUTE LEUKEMIAS OR SOLID;TUMORS Paris FRANCOIS DOZ
VADS MIBI-THYR Value of the Combination Ultrasonography With Ti-RADS Score / Dual Tracer Scintigraphy MIBI-Tc99m/Iodine-123 in the Detection of Malignancy of Thyroid Nodules (Sup or Egal to 15 mm) Classified Bethesda III or IV on Cytology. Saint-Cloud
Pédiatrie Tumeurs solides PROVIN Study of a Propranolol (HEMANGIOL®) and Oral Metronomic Vinorelbine (NAVELBINE®) Combination for Children and Teenagers With Refractory/Relapsing Solid Tumors (PROVIN) Paris ISABELLE AERTS
Recherches "plusieurs pathologies" REGOMUNE A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors Saint-Cloud SEGOLENE HESCOT
Sein métastatique RH+ SERENA-6 D8534C00001 A Phase III, Double-blind, Randomised Study to Assess Switching to AZD9833 (a Next Generation, Oral SERD) + CDK4/6 Inhibitor (Palbociclib or Abemaciclib) vs Continuing Aromatase Inhibitor (Letrozole or Anastrozole)+ CDK4/6 Inhibitor in HR+/HER2-MBC Patients With Detectable ESR1Mutation Without Disease Progression During 1L Treatment With Aromatase Inhibitor+ CDK4/6 Inhibitor- A ctDNA Guided Early Switch Study Paris, Saint-Cloud FRANCOIS-CLEMENT BIDARD, ETIENNE BRAIN
Recherches "plusieurs pathologies" MOST Plus My Own Specific Treatment : A two-period, multicenter, randomized, open-label, phase II study evaluating the clinical benefit of a maintenance treatment targeting tumor molecular alterations in patients with progressive locally-advanced or metastatic solid tumors Paris CHRISTOPHE LE TOURNEAU
Recherches "plusieurs pathologies" MK7684A-005 A Multicenter, Open-label, Phase 2 Basket Study of MK-7684A, a Co-formation of Vibostolimab (MK-7684) With Pembrolizumab (MK-3475), With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors Paris CHRISTOPHE LE TOURNEAU
Recherches "plusieurs pathologies" SCANDARE (IC 2016-03) Prospective biobanking study in ovarian, breast and head and neck cancer patients aiming at better understand the link between the molecular alterations of the tumor itself, its microenvironment and immune response. Paris, Saint-Cloud CHRISTOPHE LE TOURNEAU