Pédiatrie Rétinoblastomes RETINO-2018 (IC 2019-05) Ocular Conservative Treatment for Retinoblastoma: Efficacy of the New Management Strategies and Visual Outcome - RETINO 2018 Paris LIVIA LUMBROSO-LE ROUIC
Pédiatrie Sarcomes ZN-c3-003 A Phase 1/2 Dose Escalation and Dose Expansion Study of ZN-c3 in Combination With Gemcitabine in Adult and Pediatric Subjects With Relapsed or Refractory Osteosarcoma Paris ISABELLE AERTS
O.R.L BNT113-01 A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (AHEAD-MERIT) Paris CHRISTOPHE LE TOURNEAU
Pédiatrie Tumeurs solides MICCHADO (IC 2017-02) Molecular and Immunological Characterisation of high risk CHildhood Cancer At DiagnOsis, treatment and follow-up - Biological evaluation in children, adolescents and young adults. Paris GUDRUN SCHLEIERMACHER
Pédiatrie Tumeurs solides eSMART European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors. Paris ISABELLE AERTS
Pédiatrie Tumeurs solides METRO-PD1-1708 Metro-PD1: a phase I/II trial evaluating anti-PD1 (Nivolumab) in combination with metronomic chemotherapy in children and teenagers with refractory /relapsing solid tumors or lymphoma Paris ISABELLE AERTS
Pédiatrie Sarcomes SARCOME 13 (Pédiatrie) Multicentre, Randomised, Phase 2 Trial of Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients (Metastatic Osteosarcoma at Diagnosis or Localised Disease With Poor Histological Response) Paris HELENE PACQUEMENT
Pédiatrie Tumeurs cérébrales SIOP EPENDYMOMA II An International Clinical Program for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Ependymoma Paris FRANCOIS DOZ
Pédiatrie Tumeurs solides CDRB436G2401 An open label, multi-center roll-over study to assess longterm;effect in pediatric patients treated with Tafinlar;(dabrafenib) and/or Mekinist (trametinib) Paris FRANCOIS DOZ
Pédiatrie Sarcomes COTESARC (pédiatrie) multicentre, open-label, Phase I-II study evaluating the combination of a MEK inhibitor and a PDL1 inhibitor in pediatric and adult patients with locally advanced and/or metastatic soft tissue sarcoma Paris ISABELLE AERTS