Prostate MK3475-365 Phase Ib/II Trial of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-365) Paris
Pédiatrie Tumeurs solides LOXO-EXT-17005 A Study to Test the Safety of the Investigational Drug Loxo-195 in Children and Adults That May Treat Cancer Paris FRANCOIS DOZ
Pédiatrie Tumeurs solides D419EC00001 Phase I/II, open-label, multicentre study to evaluate the safety, tolerability, and preliminary efficacy of durvalumab monotherapy or durvalumab in combination with tremelimumab in paediatric patients with advanced solid tumours, haematological malignancies including lymphoma and acute leukaemias Paris FRANCOIS DOZ
Pédiatrie Tumeurs solides CA045-020 (PIVOT IO 020) Phase 1/2 Study of Bempegaldesleukin in Combination with Nivolumab in Children,;Adolescents, and Young Adults with Recurrent or Refractory Malignancies (PIVOT IO 020) Paris FRANCOIS DOZ
Pédiatrie Tumeurs solides GO40871 A PHASE I/II, MULTICENTER, OPEN-LABEL, MULTI-ARM;STUDY EVALUATING THE SAFETY, TOLERABILITY,;PHARMACOKINETICS, AND PRELIMINARY ACTIVITY OF;IDASANUTLIN IN COMBINATION WITH EITHER;CHEMOTHERAPY OR VENETOCLAX IN THE TREATMENT OF;PEDIATRIC AND YOUNG ADULT PATIENTS WITH;RELAPSED/REFRACTORY ACUTE LEUKEMIAS OR SOLID;TUMORS Paris FRANCOIS DOZ
Pédiatrie Sarcomes ZN-c3-003 A Phase 1/2 Dose Escalation and Dose Expansion Study of ZN-c3 in Combination With Gemcitabine in Adult and Pediatric Subjects With Relapsed or Refractory Osteosarcoma Paris ISABELLE AERTS
Sein métastatique RH+ CT7001_003 (SUMIT ELA) A Phase 1b/2 Open-label Study of Samuraciclib in Combination with Elacestrant in;Participants with Metastatic or Locally Advanced Hormone Receptor-positive and Human;Epidermal Growth Factor Receptor 2-negative Breast Cancer. Saint-Cloud FRANCOIS-CLEMENT BIDARD
Pédiatrie Tumeurs solides eSMART European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors. Paris ISABELLE AERTS
Système Nerveux Central STERIMGLI A Phase I/II Multicenter Trial Evaluating the Association of Hypofractionated Stereotactic Radiation Therapy and the Anti-Programmed Death-ligand 1 (PD-L1) Durvalumab (Medi4736) for Patients With Recurrent Glioblastoma (STERIMGLI). Saint-Cloud
Pédiatrie Sarcomes COTESARC (pédiatrie) multicentre, open-label, Phase I-II study evaluating the combination of a MEK inhibitor and a PDL1 inhibitor in pediatric and adult patients with locally advanced and/or metastatic soft tissue sarcoma Paris ISABELLE AERTS