Pédiatrie Tumeurs solides LOXO-EXT-17005 A Study to Test the Safety of the Investigational Drug Loxo-195 in Children and Adults That May Treat Cancer Paris FRANCOIS DOZ
Pédiatrie Tumeurs solides D419EC00001 Phase I/II, open-label, multicentre study to evaluate the safety, tolerability, and preliminary efficacy of durvalumab monotherapy or durvalumab in combination with tremelimumab in paediatric patients with advanced solid tumours, haematological malignancies including lymphoma and acute leukaemias Paris FRANCOIS DOZ
Sein métastatique triple négatif SYNERGY A Phase I/II Study of Paclitaxel Plus Carboplatin and Durvalumab (MEDI4736) With or Without Oleclumab (MEDI9447) for Previously Untreated Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer. Paris
Pédiatrie Tumeurs solides CA045-020 (PIVOT IO 020) Phase 1/2 Study of Bempegaldesleukin in Combination with Nivolumab in Children,;Adolescents, and Young Adults with Recurrent or Refractory Malignancies (PIVOT IO 020) Paris FRANCOIS DOZ
Gynécologie GYNET A Randomized, Multicenter, Open Label, Phase I/II Study to Evaluate the Safety, Clinical and Biological Activity of a Humanized Monoclonal Antibody Targeting Netrin-1 (NP137) in Combination With Carboplatin Plus Paclitaxel and/or Pembrolizumab in Patients With Locally Advanced/Metastatic Endometrial Carcinoma or Cervix Carcinoma Progressing/Relapsing After at Least One Prior Systemic Chemotherapy. Saint-Cloud
Pédiatrie Tumeurs solides eSMART European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors. Paris ISABELLE AERTS
Pédiatrie Tumeurs solides GO40871 A PHASE I/II, MULTICENTER, OPEN-LABEL, MULTI-ARM;STUDY EVALUATING THE SAFETY, TOLERABILITY,;PHARMACOKINETICS, AND PRELIMINARY ACTIVITY OF;IDASANUTLIN IN COMBINATION WITH EITHER;CHEMOTHERAPY OR VENETOCLAX IN THE TREATMENT OF;PEDIATRIC AND YOUNG ADULT PATIENTS WITH;RELAPSED/REFRACTORY ACUTE LEUKEMIAS OR SOLID;TUMORS Paris FRANCOIS DOZ
Pédiatrie Tumeurs solides INFORM2 - NIVENT (IC 2018-07) INFORM2 Exploratory Multinational Phase I/II Combination Study of Nivolumab and Entinostat in Children and Adolescents With Refractory High-risk Malignancies Paris GUDRUN SCHLEIERMACHER
Pédiatrie Tumeurs solides iMATRIX-Alectinib (GO42286) A Phase I/II, Open-Label, Multicenter, Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Patients With ALK Fusion-Positive Solid or CNS Tumors for Whom Prior Treatment Has Proven to be Ineffective or for Whom There is No Satisfactory Treatment Available. Paris FRANCOIS DOZ