Alain PUISIEUX

Professeur,
Professeur des universités-praticien hospitalier UVSQ
Recherche - Paris
Spécialités / domaines
Cancer,
Hétérogénéité,
Instabilité,
Plasticité
Functions within Institut Curie:
  • Researcher
    Chemical Biology of Cancer
    Unit : Cellular and Chemical Biology (UMR3666 / U1143)
  • Director
    Direction du Centre de Recherche
Présentation

Prof. Alain Puisieux has been Director of the Research Center of the Institut Curie since September 2019. 

His vision is driven by the conviction that upcoming advances in biomedical research will stem from a better understanding of mechanisms that govern fundamental biological processes. In this context, he strongly supports basic research in the life sciences by promoting thematic diversity and interdisciplinarity and stimulates the research-care continuum by strengthening the links between the Research Center and the Hospital Group of the Institut Curie.

Concomitant with his Director duties, Prof. Alain Puisieux has over 20 years of experience heading oncological research in France. Notably, he has been Director of Basic Research at Centre Léon Berard (Lyon) from 2001 to 2019 and Director of the Research Center in Cancerology of Lyon (CRCL) from 2011 to 2019.  Alain’s leadership has led to the creation of several prestigious national foundations and scientific networks dedicated to cancer research. His scientific activity has largely contributed to unravelling the role of cellular plasticity in early steps of tumorigenesis. As full professor, he is also actively involved in providing training to students at University of Versailles Saint-Quentin-en-Yvelines (UVSQ) and Lyon 1 University in diverse fields such as Oncology, Biochemistry and Molecular Biology.

Prof. Alain Puisieux is a Member of the French National Academy of Medicine and the French National Academy of Pharmacy, as well as a former member of the French University Institute (IUF). He has been made Knight of the Order of Academic Palms in 2015 (French Ministry of National Education, Higher Education and Research) and has been appointed Knight of the Legion of Honour in 2021. He has received several prestigious scientific awards, including the Duquesne Prize (2019), the Ruban Rose Grand Prize for Breast Cancer Research (2018), and the Dandrimont- Bénicourt Prize from the French National Academy of Sciences (2017). 

Publications
LifeTime and improving European healthcare through cell-based interceptive medicine
Nature
Nikolaus Rajewsky, Geneviève Almouzni, Stanislaw A. Gorski, Stein Aerts, Ido Amit, Michela G. Bertero, Christoph Bock, Annelien L. Bredenoord, Giacomo Cavalli, Susanna Chiocca, Hans Clevers, Bart De Strooper, Angelika Eggert, Jan Ellenberg, Xosé M. Fernández, Marek Figlerowicz, Susan M. Gasser, Norbert Hubner, Jørgen Kjems, Jürgen A. Knoblich, Grietje Krabbe, Peter Lichter, Sten Linnarsson, Jean-Christophe Marine, John C. Marioni, Marc A. Marti-Renom, Mihai G. Netea, Dörthe Nickel, Marcelo Nollmann, Halina R. Novak, Helen Parkinson, Stefano Piccolo, Inês Pinheiro, Ana Pombo, Christian Popp, Wolf Reik, Sergio Roman-Roman, Philip Rosenstiel, Joachim L. Schultze, Oliver Stegle, Amos Tanay, Giuseppe Testa, Dimitris Thanos, Fabian J. Theis, Maria-Elena Torres-Padilla, Alfonso Valencia, Céline Vallot, Alexander van Oudenaarden, Marie Vidal, Thierry Voet, Lavinia Alberi, Stephanie Alexander, Theodore Alexandrov, Ernest Arenas, Claudia Bagni, Robert Balderas, Andrea Bandelli, Burkhard Becher, Matthias Becker, Niko Beerenwinkel, Monsef Benkirame, Marc Beyer, Wendy Bickmore, Erik E. A. L. Biessen, Niklas Blomberg, Ingmar Blumcke, Bernd Bodenmiller, Barbara Borroni, Dimitrios T. Boumpas, Thomas Bourgeron, Sarion Bowers, Dries Braeken, Catherine Brooksbank, Nils Brose, Hilgo Bruining, Jo Bury, Nicolo Caporale, Giorgio Cattoretti, Nadia Chabane, Hervé Chneiweiss, Stuart A. Cook, Paolo Curatolo, Marien I. de Jonge, Bart Deplancke, Bart De Strooper, Peter de Witte, Stefanie Dimmeler, Bogdan Draganski, Anna Drews, Costica Dumbrava, Stefan Engelhardt, Thomas Gasser, Evangelos J. Giamarellos-Bourboulis, Caroline Graff, Dominic Grün, Ivo Gut, Oskar Hansson, David C. Henshall, Anna Herland, Peter Heutink, Stephane R. B. Heymans, Holger Heyn, Meritxell Huch, Inge Huitinga, Paulina Jackowiak, Karin R. Jongsma, Laurent Journot, Jan Philipp Junker, Shauna Katz, Jeanne Kehren, Stefan Kempa, Paulus Kirchhof, Christine Klein, Natalia Koralewska, Jan O. Korbel, Malte Kühnemund, Angus I. Lamond, Elsa Lauwers, Isabelle Le Ber, Ville Leinonen, Alejandro Lopez Tobon, Emma Lundberg, Astrid Lunkes, Henrike Maatz, Matthias Mann, Luca Marelli, Vera Matser, Paul M. Matthews, Fatima Mechta-Grigoriou, Radhika Menon, Anne F. Nielsen, Massimiliano Pagani, R. Jeroen Pasterkamp, Asla Pitkänen, Valentin Popescu, Cyril Pottier, Alain Puisieux, Rosa Rademakers, Dory Reiling, Orly Reiner, Daniel Remondini, Craig Ritchie, Jonathan D. Rohrer, Antoine-Emmanuel Saliba, Raquel Sanchez-Valle, Amedeo Santosuosso, Arnold Sauter, Richard A. Scheltema, Philip Scheltens, Herbert B. Schiller, Anja Schneider, Philip Seibler, Kelly Sheehan-Rooney, David Shields, Kristel Sleegers, August B. Smit, Kenneth G. C. Smith, Ilse Smolders, Matthis Synofzik, Wai Long Tam, Sarah Teichmann, Maria Thom, Margherita Y. Turco, Heleen M. M. van Beusekom, Rik Vandenberghe, Silvie Van den Hoecke, Ibo Van de Poel, Andre van der Ven, Julie van der Zee, Jan van Lunzen, Geert van Minnebruggen, Alexander van Oudenaarden, Wim Van Paesschen, John van Swieten, Remko van Vught, Matthijs Verhage, Patrik Verstreken, Carlo Emanuele Villa, Jörg Vogel, Christof von Kalle, Jörn Walter, Sarah Weckhuysen, Wilko Weichert, Louisa Wood, Anette-Gabriele Ziegler, Frauke Zipp,
Guidelines and definitions for research on epithelial–mesenchymal transition
Nature Reviews Molecular Cell Biology
Jing Yang, Parker Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz, Marianne Bronner, Kyra Campbell, Amparo Cano, Jordi Casanova, Gerhard Christofori, Shoukat Dedhar, Rik Derynck, Heide L. Ford, Jonas Fuxe, Antonio García de Herreros, Gregory J. Goodall, Anna-Katerina Hadjantonakis, Ruby Y. J. Huang, Chaya Kalcheim, Raghu Kalluri, Yibin Kang, Yeesim Khew-Goodall, Herbert Levine, Jinsong Liu, Gregory D. Longmore, Sendurai A. Mani, Joan Massagué, Roberto Mayor, David McClay, Keith E. Mostov, Donald F. Newgreen, M. Angela Nieto, Alain Puisieux, Raymond Runyan, Pierre Savagner, Ben Stanger, Marc P. Stemmler, Yoshiko Takahashi, Masatoshi Takeichi, Eric Theveneau, Jean Paul Thiery, Erik W. Thompson, Robert A. Weinberg, Elizabeth D. Williams, Jianhua Xing, Binhua P. Zhou, Guojun Sheng,
Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma
Clinical Cancer Research
Mathieu Chicard, Sandrine Boyault, Leo Colmet Daage, Wilfrid Richer, David Gentien, Gaelle Pierron, Eve Lapouble, Angela Bellini, Nathalie Clement, Isabelle Iacono, Stéphanie Bréjon, Marjorie Carrere, Cécile Reyes, Toby Hocking, Virginie Bernard, Michel Peuchmaur, Nadège Corradini, Cécile Faure-Conter, Carole Coze, Dominique Plantaz, Anne Sophie Defachelles, Estelle Thebaud, Marion Gambart, Frédéric Millot, Dominique Valteau-Couanet, Jean Michon, Alain Puisieux, Olivier Delattre, Valérie Combaret, Gudrun Schleiermacher
Influence of Nucleoshuttling of the ATM Protein in the Healthy Tissues Response to Radiation Therapy: Toward a Molecular Classification of Human Radiosensitivity
International Journal of Radiation Oncology*Biology*Physics
Adeline Granzotto, Mohamed Amine Benadjaoud, Guillaume Vogin, Clément Devic, Mélanie L. Ferlazzo, Larry Bodgi, Sandrine Pereira, Laurène Sonzogni, Fabien Forcheron, Muriel Viau, Aurélie Etaix, Karim Malek, Laurence Mengue-Bindjeme, Clémence Escoffier, Isabelle Rouvet, Marie-Thérèse Zabot, Aurélie Joubert, Anne Vincent, Nicole Dalla Venezia, Michel Bourguignon, Edme-Philippe Canat, Anne d'Hombres, Estelle Thébaud, Daniel Orbach, Dominique Stoppa-Lyonnet, Abderraouf Radji, Eric Doré, Yoann Pointreau, Céline Bourgier, Pierre Leblond, Anne-Sophie Defachelles, Cyril Lervat, Stéphanie Guey, Loic Feuvret, Françoise Gilsoul, Claire Berger, Coralie Moncharmont, Guy de Laroche, Marie-Virginie Moreau-Claeys, Nicole Chavaudra, Patrick Combemale, Marie-Claude Biston, Claude Malet, Isabelle Martel-Lafay, Cécile Laude, Ngoc-Hanh Hau-Desbat, Amira Ziouéche, Ronan Tanguy, Marie-Pierre Sunyach, Séverine Racadot, Pascal Pommier, Line Claude, Frédéric Baleydier, Bertrand Fleury, Renaud de Crevoisier, Jean-Marc Simon, Pierre Verrelle, Didier Peiffert, Yazid Belkacemi, Jean Bourhis, Eric Lartigau, Christian Carrie, Florent De Vathaire, François Eschwege, Alain Puisieux, Jean-Léon Lagrange, Jacques Balosso, Nicolas Foray