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- GSK 219451 - POPSTAR
GSK 219451 - POPSTAR
Phase 1/2 Dose Determination and Dose Expansion Study of Cobolimab in Combination with Dostarlimab in Pediatric and Young Adult Participants with Newly Diagnosed and Relapsed/Refractory Tumors (POPSTAR).
- Open at Paris since : 30/05/2025
- Target : Child
- Phase : Phase II
Trial description
Phase 1:;To assess the safety and tolerability of cobolimab in combination with dostarlimab in pediatric and young adult participants with relapsed/refractory or newly diagnosed tumors.;To determine the recommended Phase 2 dose (RP2D) for the combination.;Phase 2:;To evaluate the anti-tumor activity of the combination based on objective response rate (ORR) per RECIST or other appropriate criteria.
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