TROPION LUNG 14

In the preliminary safety evaluation phase, how does the participants' health status evolve during the trial?;In the preliminary safety evaluation phase, the researchers will record all medical issues (adverse events) that occur during the trial. They will also examine the results of various tests and measurements to assess whether the participantsÀ health status changes after starting the investigational treatment.;In the randomized part of the trial, does treatment with Dato-DXd and osimertinib help participants live longer without their tumor growing or spreading compared to osimertinib alone?;In the randomized part of the trial, an independent review committee will examine participantsÀ imaging separately from the trial physicians. Then, the researchers will track how long participants live without their tumor growing or spreading after starting treatment À this is called progression-free survival (PFS).