- Deputy Director of Research Unit
- Coordinateur de site
Fatima Mechta-Grigoriou, PhD in Science specialized in Cancer Biology. She is Research Director of Exceptional Class at Inserm and Director of the “Stress and Cancer” laboratory at Institut Curie. She is also the deputy director of the research unit U830, Cancer, Heterogeneity, Instability and Plasticity at Curie Institute and has recently been nominated the Scientific Director of the Cancéropôle Ile de France.
She is an internationally recognized expert investigating the impact of tumor heterogeneity in immunosuppression, metastatic spread and resistance to treatment. Her lab has identified different fibroblast (CAF) populations in several cancers, such as breast, ovarian and lung cancer and revealed that some specific CAF are involved in immunosuppression and resistance to immunotherapies. Her lab also demonstrated the paradoxical effects of Reactive Oxygen Species. Although they are involved in tumor growth and spread, they can also improve sensitivity to chemotherapy.
She received several awards, such as the Rosen Prize 2021, the Grand Prize of the Foundation Del Duca 2018 and the Grand Prize of the Pink Ribbon 2017.