Base-Catalyzed Transcarbamoylation

1 Sept 2017Synlett

DOI : 10.1055/s-0036-1588866

Authors

Vincent Semetey, Benoît Rhoné

Abstract

Inorganic bases such as NaH, KOt-Bu, NaOH, or KOH are efficient catalysts to promote the transcarbamoylation reaction between urethanes and a variety of primary and secondary alcohols under mild conditions. They constitute an alternative to organometallic catalysis and can be applied to aliphatic or aromatic urethanes.