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  • Diacylglycerol kinase ΞΆ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse

Diacylglycerol kinase ΞΆ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse

14 Apr 2020Science Signaling

DOI : 10.1126/scisignal.aaw8214

Authors

Sara V. Merino-CortΓ©s, Sofia R. Gardeta, Sara Roman-Garcia, Ana MartΓ­nez-RiaΓ±o, Judith Pineau, Rosa Liebana, Isabel Merida, Ana-Maria Lennon Dumenil, Paolo Pierobon, Julien Husson, Balbino Alarcon, Yolanda R. Carrasco

Abstract

Optimal B cell responses depend on balanced signaling between DAG and phosphatidic acid, which is regulated by diacylglycerol kinase ΞΆ.

Members

ANA-MARIA LENNON DUMENIL

Directeur de recherche Inserm