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Identification of MRC2 and CD209 receptors as targets for photodynamic therapy of retinoblastoma using mesoporous silica nanoparticles

1 Jan 2015RSC Advances

DOI : 10.1039/c5ra14640b

Authors

A. Gallud, D. Warther, M. Maynadier, M. Sefta, F. Poyer, C. D. Thomas, C. Rouxel, O. Mongin, M. Blanchard-Desce, A. Morère, L. Raehm, P. Maillard, J. O. Durand, M. Garcia, M. Gary-Bobo

Abstract

An overexpression of MRC2 and CD209 mannose receptors was revealed in retinoblastoma and antibodies against these receptors were grafted to multifunctional nanoparticles for targeting of imaging and photodynamic therapy.