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- Iron-dependent lysosomal dysfunction mediated by a natural product hybrid
Iron-dependent lysosomal dysfunction mediated by a natural product hybrid
Authors
A. Mariani, T. T. Mai, E. Zacharioudakis, A. Hienzsch, A. Bartoli, T. Cañeque, R. Rodriguez
Abstract
Marmycin A and artemisinin join forces as the molecular hybrid artesumycin, a new fluorescent lysosomotropic small molecule that targets lysosomal iron to kill cancer cells.
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