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LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

5 Jul 2019Science Advances

Authors

Anca G. Radu, Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas, Uwe Schlattner, Laurence Lafanechère, Pierre Hainaut, Nicolas Tricaud, Véronique Pingault, Nadège Bondurand, Nabeel Bardeesy, Lionel Larue, Chantal Thibert, Marc Billaud

Abstract

Glial specification of neural crest cells requires the tumor suppressor LKB1-mediated action on alanine biosynthesis.

Members

LIONEL LARUE

Inserm Research Director