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Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication

29 May 2020Science Advances

DOI : 10.1126/sciadv.aaz4126

Authors

L. Boeckemeier, R. Kraehenbuehl, A. Keszthelyi, M. U. Gasasira, E. G. Vernon, R. Beardmore, C. B. Vågbø, D. Chaplin, S. Gollins, H. E. Krokan, S. A. E. Lambert, B. Paizs, E. Hartsuiker

Abstract

Mre11 exonuclease activity removes gemcitabine from the nascent strand during DNA replication.

Members

SARAH LAMBERT

Directeur de recherche CNRS