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Probing ligand and cation binding sites in G-quadruplex nucleic acids by mass spectrometry and electron photodetachment dissociation sequencing

1 Jan 2019The Analyst

DOI : 10.1039/c9an00398c

Authors

Dababrata Paul, Adrien Marchand, Daniela Verga, Marie-Paule Teulade-Fichou, Sophie Bombard, Frédéric Rosu, Valérie Gabelica

Abstract

Tandem mass spectrometry: native top-down sequencing by electron photodetachment dissociation (EPD) reveals ligand binding sites on DNA G-quadruplexes.