Quadruplex DNA-guided ligand selection from dynamic combinatorial libraries of acylhydrazones
Nom de la revue
Organic & Biomolecular Chemistry
Abstract
Synthesis of dynamic combinatorial libraries of acylhydrazones in the presence of a G-quadruplex DNA template, followed by pull-down with streptavidin-coated magnetic beads, allows the identification of putative G-quadruplex binders.
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