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Quantifying nanotherapeutic penetration using a hydrogel-based microsystem as a new 3D in vitro platform

Quantifying nanotherapeutic penetration using a hydrogel-based microsystem as a new 3D in vitro platform

1 Jan 2021Lab on a Chip

Authors

Saba Goodarzi, Audrey Prunet, Fabien Rossetti, Guillaume Bort, Olivier Tillement, Erika Porcel, Sandrine Lacombe, Ting-Di Wu, Jean-Luc Guerquin-Kern, Hélène Delanoë-Ayari, François Lux, Charlotte Rivière

Abstract

We present a simple yet highly flexible 3D-model microsystem for the investigation of nanotherapeutics transport, ahead of in vivo studies, allowing to follow the penetration and distribution of nanoparticles within spheroids over space and time.

Members

TING-DI WU

Ingénieur de recherche Inserm

GUILLAUME BORT

CNRS Researcher