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9 result(s)

2025Mechanisms and regulation of DNA end resection in the maintenance of genome stabilityNature Reviews Molecular Cell Biology
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2025Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumorsMolecular Cell
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2023DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/CMolecular Cell
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2023Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosisNature
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2021A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumorsNature Cancer
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2016FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA RepairCell Reports
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2016Repair Pathway Choices and Consequences at the Double-Strand BreakTrends in Cell Biology
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2015Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian CancerCancer Discovery
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2015Homologous-recombination-deficient tumours are dependent on Polθ-mediated repairNature
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