Formation and remodeling of tubular networks in the mouse pancreas and in organoids

Anne Grapin-Botton has a background in developmental biology and initially studied nervous system and endoderm development. Her laboratory is currently focusing on pancreas development with the overall goals of understanding how pancreatic cells differentiate during embryogenesis, and determining what limits the pancreatic cells’ regeneration in adults. More specifically, Professor Grapin-Botton and her group investigate the impact of the cellular and organ architecture on the cells’ fate choices and the dynamics of decision processes.