Institut Curie Research Center
Institut Curie is one of the largest European institutions for cancer and biomedical research, with strong interdisciplinary traditions. It comprises a hospital and a Research Center with more than 3,500 researchers, physicians, and healthcare staff, and has strong international representation around its three missions: patient care, research, and education. It is located across three main sites, in central Paris, St. Cloud, and Orsay, France, within a culturally and scientifically rich environment. The main objective of the Institut Curie Research Center is to develop fundamental research and to use the knowledge generated to improve cancer diagnosis, prognosis, and therapy, within a continuum linking basic research to innovation for the benefit of patients.
Laboratory - CellAction
CellAction is part of Institut Curie’s commitment to building unique expertise in cell and gene therapy. It integrates multidisciplinary competencies in bioinformatics, target discovery and validation, molecular biology, genome editing, viral and non-viral vector design, cell engineering, and the development of in vitro and in vivo tumor models for cell and gene therapy applications. Furthermore, CellAction provides pre-GMP process development expertise, aiming to generate fully characterized, GMP-ready cell therapy products that can be manufactured in dedicated GMP facilities and subsequently evaluated in clinical settings.
In 2025, CellAction was permanently established at the Saint-Cloud site of Institut Curie.
At the Process Development group at CellAction, our activities focus on the development and optimization of manufacturing processes for cell- and gene-based therapies, ensuring translational feasibility and compliance with regulatory standards for clinical-grade production.
https://curie.fr/cellaction-un-laboratoire-unique-pour-lacces-aux-therapies-cellulaires-et-geniques
Missions / Responsibilities
· Develop, optimize, and adapt manufacturing processes for cell and gene therapies, including viral/non-viral vectors and genome editing.
· Develop analytical methods for product characterization, viability, purity, and potency.
· Monitor critical process parameters and product quality attributes.
· Collaborate with multidisciplinary teams, communicate results, and contribute to troubleshooting.
· Prepare technical reports, SOPs, and development documentation in compliance with regulatory requirements.
· Identify opportunities to improve processes, optimize costs, and increase efficiency.
· Stay up to date with emerging technologies in cell and gene therapy.
What We Offer
- Opportunity to work on cutting-edge therapies
- Dynamic and collaborative environment
- Competitive salary and benefits package
- Career development opportunities
- Master's degree in Biotechnology, Biochemical Engineering, or related field
- 2–5 years of experience in process development (cell therapy, gene therapy, or drug development)
Preferred Qualifications
• Demonstrated proficiency in aseptic mammalian cell culture, with preference for experience in primary T-cell culture, cell activation, and cell expansion systems, viral transduction techniques, immunophenotyping (e.g. Flow cytometry)
• Knowledge of analytical characterization and critical quality attributes (CQAs), preferably for cell and gene therapy drug products, including titer, purity, potency, and sterility.
• Hands-on experience with site-specific gene-editing technologies (e.g., CRISPR-Cas) is desirable; however, it is not mandatory.
• Excellent written and verbal communication skills, with the ability to clearly present technical and scientific information to multidisciplinary teams.
• Knowledge of GMP environment and regulatory expectations is desirable; however, it is not mandatory.
• Analytical and problem-solving skills
• Ability to work in a multidisciplinary and fast-paced environment
• Fluent in English; French is a plus
Required Skills and Competencies
• Ability to work independently in managing routine tasks
• Good communication skills
• Strong organizational skills
• Adaptability and responsiveness
• Ability to work effectively as part of a team
All our opportunities are open to individuals with disabilities
Contract Information
Contract type: Fixed-term contract (CDD)
Start date: As soon as possible
Contract duration: 6 months, renewable for an additional 12 months
Working time: Full-time – 39 hours per week
Salary: 30396€ à 33013€/year according to current salary scales
Benefits: Company cafeteria, 70% coverage of annual public transportation pass, company health insurance
Location: Saint-Cloud
Contact
Please send your CV and cover letter
Date de parution de l'offre : 25/09/2026
Date limite des candidatures : Once filled
Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf