RAPHAEL LABRUERE

After studying biochemistry/chemistry (Paris Descartes and Paris Diderot universities), he obtained his PhD in chemistry in December 2006 (organic and medicinal chemistry of antivascular azalignans under the supervision of Pr. S. Giorgi-Renault, University Paris Descartes, Faculty of Pharmacy). Then he moved to the U.S. as a postdoctoral researcher on a two-year contract (group of Prof. E. Turos; University of South Florida), where he developed polymeric nanoparticles as drug delivery vehicles. In October 2010, after a year as lecturer in therapeutic chemistry (chemoenzymatic synthesis; group of Prof. M. Vidal, University Paris Descartes, Faculty of Pharmacy), he then worked on kinetically tunable self-immolative spacers as optical syringe for biological applications (collaborative project between Institut Curie and Ecole normale supérieure-Paris under the supervision of Dr. F. Schmidt and Prof. L. Jullien). Appointed as Assistant Professor (Maître de Conférences) at University Paris-Saclay in September 2013, his expertise covers heterocyclic synthesis and pharmacological evaluation of small molecules (drugs and prodrugs), and the synthesis and kinetic study of quinone methide-based self-immolative spacers.