GIORGIO SEANO

Doctor,

Tenured Research Scientist CNRS

Recherche - Orsay

Spécialités / domaines

Biology,

Integrative tumor biology, immunology and environment,

Translational research

Functions within Institut Curie:

Team Leader

Tumor Microenvironment
Unit : Signaling, radiobiology and cancer (UMR3347 / U1021)

Publications

2021

Dual Role of Integrin Alpha-6 in Glioblastoma: Supporting Stemness in Proneural Stem-Like Cells While Inducing Radioresistance in Mesenchymal Stem-Like Cells

Cancers

Elisabetta Stanzani, Leire Pedrosa, Guillaume Bourmeau, Oceane Anezo, Aleix Noguera-Castells, Anna Esteve-Codina, Lorena Passoni, Michela Matteoli, Núria de la Iglesia, Giorgio Seano, Fina Martínez-Soler, Avelina Tortosa

(2021 19 Jun)

2020

In vivo compression and imaging in mouse brain to measure the effects of solid stress

Nature Protocols

Hadi T. Nia, Meenal Datta, Giorgio Seano, Sue Zhang, William W. Ho, Sylvie Roberge, Peigen Huang, Lance L. Munn, Rakesh K. Jain

(2020 01 Aug)

2020

Vessel co-option in glioblastoma: emerging insights and opportunities

Angiogenesis

Giorgio Seano, Rakesh K. Jain

(2020 01 Feb)

2019

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

Nature Biomedical Engineering

Giorgio Seano, Hadi T. Nia, Kyrre E. Emblem, Meenal Datta, Jun Ren, Shanmugarajan Krishnan, Jonas Kloepper, Marco C. Pinho, William W. Ho, Mitrajit Ghosh, Vasileios Askoxylakis, Gino B. Ferraro, Lars Riedemann, Elizabeth R. Gerstner, Tracy T. Batchelor, Patrick Y. Wen, Nancy U. Lin, Alan J. Grodzinsky, Dai Fukumura, Peigen Huang, James W. Baish, Timothy P. Padera, Lance L. Munn, Rakesh K. Jain

(2019 01 Mar)

2019

Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges

Annual Review of Physiology

John D. Martin, Giorgio Seano, Rakesh K. Jain

(2019 10 Feb)

2018

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

Cancer Cell

Amelie Griveau, Giorgio Seano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K. Sabo, Nancy Wang, Ivy Chen, Jonas Kloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L. Suvà, Joanna J. Phillips, Manish K. Aghi, Shwetal Mehta, Rakesh K. Jain, David H. Rowitch

(2018 01 May)

2018

Quantifying solid stress and elastic energy from excised or in situ tumors

Nature Protocols

Hadi T Nia, Meenal Datta, Giorgio Seano, Peigen Huang, Lance L Munn, Rakesh K Jain

(2018 01 May)

2018

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

Science

Ethel R. Pereira, Dmitriy Kedrin, Giorgio Seano, Olivia Gautier, Eelco F. J. Meijer, Dennis Jones, Shan-Min Chin, Shuji Kitahara, Echoe M. Bouta, Jonathan Chang, Elizabeth Beech, Han-Sin Jeong, Michael C. Carroll, Alphonse G. Taghian, Timothy P. Padera

(2018 23 Mar)

2018

Vascular beds maintain pancreatic tumour explants for ex vivo drug screening

Journal of Tissue Engineering and Regenerative Medicine

Despina Bazou, Nir Maimon, Gabriel Gruionu, Jelena Grahovac, Giorgio Seano, Hao Liu, Conor L. Evans, Lance L. Munn

(2018 01 Jan)

2018

Targeting the perivascular niche in brain tumors

Current Opinion in Oncology

Giorgio Seano

(2018 01 Jan)