MARIA CARLA PARRINI

Recherche - Paris

Spécialités / domaines

Cell biology,

Cancer,

Cellular and Tissue Imaging,

Signalling

Functions within Institut Curie:

Research Engineer

Stress and cancer
Unit : Cancer, Heterogeneity, Instability and Plasticity - CHIP (U830)

Présentation

MC Parrini joined the Institut Curie in 2003. She was a driving force in the initiation and realization of several interdisciplinary collaborations at the interface between cell biology, clinical oncology, biophysics, computer science, and industrial partners. She developed and applied innovative approaches to study cancer cell biology: biosensors, optogenetics, computational methods, and microfabrication/microfluidics. She is a recognized pioneer in the tumor-on-chip technology field.

Publications

2022

Direct imaging and automatic analysis in tumor-on-chip reveal cooperative antitumoral activity of immune cells and oncolytic vaccinia virus

Biosensors and Bioelectronics

Arianna Mencattini, Christine Lansche, Irina Veith, Philippe Erbs, Jean-Marc Balloul, Eric Quemeneur, Stéphanie Descroix, Fatima Mechta-Grigoriou, Gérard Zalcman, Cécile Zaupa, Maria Carla Parrini, Eugenio Martinelli

(2022 01 Nov)

2022

Precise and fast control of the dissolved oxygen level for tumor-on-chip

Lab on a Chip

Charlotte Bouquerel, William César, Lara Barthod, Sarah Arrak, Aude Battistella, Giacomo Gropplero, Fatima Mechta-Grigoriou, Gérard Zalcman, Maria Carla Parrini, Marine Verhulsel, Stéphanie Descroix

(2022 01 Jan)

2021

Autophagy Is Polarized toward Cell Front during Migration and Spatially Perturbed by Oncogenic Ras

Cells

Manish Kumar Singh, Giulia Zago, Irina Veith, Jacques Camonis, Mathieu Coppey, Maria Carla Parrini

(2021 02 Oct)

2021

Recursive Deep Prior Video: A super resolution algorithm for time-lapse microscopy of organ-on-chip experiments

Medical Image Analysis

Pasquale Cascarano, Maria Colomba Comes, Arianna Mencattini, Maria Carla Parrini, Elena Loli Piccolomini, Eugenio Martinelli

(2021 01 Aug)

2021

Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death

PLOS Computational Biology

Irina Veith, Arianna Mencattini, Valentin Picant, Marco Serra, Marine Leclerc, Maria Colomba Comes, Fathia Mami-Chouaib, Jacques Camonis, Stéphanie Descroix, Hamasseh Shirvani, Fatima Mechta-Grigoriou, Gérard Zalcman, Maria Carla Parrini, Eugenio Martinelli

(2021 30 Mar)

2021

In vitro bone metastasis dwelling in a 3D bioengineered niche

Biomaterials

Weijing Han, Rania El Botty, Elodie Montaudon, Laurent Malaquin, Frederic Deschaseaux, Nicolas Espagnolle, Elisabetta Marangoni, Paul Cottu, Gérard Zalcman, Maria Carla Parrini, Franck Assayag, Luc Sensebe, Pascal Silberzan, Anne Vincent-Salomon, Guillaume Dutertre, Sergio Roman-Roman, Stephanie Descroix, Jacques Camonis

(2021 01 Feb)

2020

Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms

Nature Communications

Floriane Pelon, Brigitte Bourachot, Yann Kieffer, Ilaria Magagna, Fanny Mermet-Meillon, Isabelle Bonnet, Ana Costa, Anne-Marie Givel, Youmna Attieh, Jorge Barbazan, Claire Bonneau, Laetitia Fuhrmann, Stéphanie Descroix, Danijela Vignjevic, Pascal Silberzan, Maria Carla Parrini, Anne Vincent-Salomon, Fatima Mechta-Grigoriou

(2020 01 Dec)

2020

Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments

Scientific Reports

A. Mencattini, D. Di Giuseppe, M. C. Comes, P. Casti, F. Corsi, F. R. Bertani, L. Ghibelli, L. Businaro, C. Di Natale, M. C. Parrini, E. Martinelli

(2020 01 Dec)

2019

The influence of spatial and temporal resolutions on the analysis of cell-cell interaction: a systematic study for time-lapse microscopy applications

Scientific Reports

M. C. Comes, P. Casti, A. Mencattini, D. Di Giuseppe, F. Mermet-Meillon, A. De Ninno, M. C. Parrini, L. Businaro, C. Di Natale, E. Martinelli

(2019 01 Dec)

2019

Localization of RalB signaling at endomembrane compartments and its modulation by autophagy

Scientific Reports

Manish Kumar Singh, Alexandre P. J. Martin, Carine Joffre, Giulia Zago, Jacques Camonis, Mathieu Coppey, Maria Carla Parrini

(2019 01 Dec)