Recherche - Orsay
Spécialités / domaines
Biologie et chimie des radiations, signalisation cellulaire et cancer

Nathalie is a former student of “l’école normale supérieure de Cachan” (now called Paris-Saclay) within the Biochemistry department. She completed her doctoral training at the Institut Pasteur/Institut de Biologie de Lille where she worked on oncogenic transcription factors and their role in cell differentiation during embryonic development, and earned a Ph.D. in Fundamental Bases of Oncogenesis from the Université Denis Diderot (now called Université de Paris) in 1999. She then performed a post-doctoral training at institut Curie at Orsay where she worked on a similar thematic. Following a second post-doctoral training at the hospital la Pitié-Salpétrière in Paris, on the role of transcription factors during neuronal differentiation, she was recruited as a Lecturer in the Biochemistry department of the Université Denis Diderot, and integrated a team to work on secreted proteins, deregulated in various cancers. In 2008, she came back to the institut Curie at Orsay and worked on a phosphatase involved in ocular melanoma cell migration, before joining the team in 2020. Her works now focus on transcription factors, potential targets of microRNAs in some subgroups of medulloblastomas.

High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Cancer Research
Cécile Laurent, Fabien Valet, Nathalie Planque, Licia Silveri, Selma Maacha, Océane Anezo, Philippe Hupe, Corine Plancher, Cécile Reyes, Benoit Albaud, Audrey Rapinat, David Gentien, Jérôme Couturier, Xavier Sastre-Garau, Laurence Desjardins, Jean-Paul Thiery, Sergio Roman-Roman, Bernard Asselain, Emmanuel Barillot, Sophie Piperno-Neumann, Simon Saule