Unit
Signaling, radiobiology and cancer (UMR3347 / U1021)
Thematic areas of research:
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Unit
ARTURO LONDONO / LIONEL LARUE
Signaling, radiobiology and cancer (UMR3347 / U1021)
The cornerstone of our unit’s research thematic is its integrative view of molecular and cellular knowledge in a physiopathological context, ultimately favoring the development of innovative treatments for cancer. The unit, located on the Orsay site of the Institut Curie Research Center, has a significant critical mass, and the focusing of its interests on a main axis of research lead to the development of synergy and foster innovation and creativity
Teams
Key figures
25
publications in 2020
2
ongoing ERC in 2020
16
PhD students in 2020
Key publications
All publications
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X-rays minibeam radiation therapy at a conventional irradiator: Pilot evaluation in F98-glioma bearing rats and dose calculations in a human phantomClinical and Translational Radiation Oncology
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AsiDNA Is a Radiosensitizer with no Added Toxicity in Medulloblastoma Pediatric ModelsClinical Cancer Research
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News
All news
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Improved understanding of the molecular mechanisms of the side effects caused by radiotherapyAlthough radiotherapy saves increasing numbers of cancer patients, at the same time we are seeing more side effects. A team from Institut Curie sought to better understand the mechanisms of lesions caused by this gold standard treatment.15/06/2023 -
Yolanda Prezado, Carsten Janke, Céline Vallot et Nicolas Manel récompensés par l’Académie des sciencesLe 23 novembre, l’Académie des sciences a remis, lors d'une cérémonie exceptionnelle sous la coupole de l’Institut de France, l’ensemble des prix et médailles qu’elle a attribués en 2021. Quatre chercheurs et médecins de l’Institut Curie ont été distingués. Toutes nos félicitations !25/11/2021 -
Rétinoblastome : un projet ambitieux pour préserver la vision des enfantsL’Institut Curie, centre de référence pour le rétinoblastome, cancer pédiatrique de l’œil le plus fréquent, s’apprête à démarrer un projet de recherche pluridisciplinaire qui impliquera plusieurs de ses équipes de recherche et services hospitaliers.18/11/2021 -
FHL3: A Scaffold Protein, Architect of the Embryonic Nervous SystemThe various signals that orchestrate the first notes of the concerto that is the nervous system are part of a very complex score! Even so, researchers from Institut Curie, CNRS, Inserm, and Université Paris-Saclay* have managed to decipher the role played by FHL3, a modulator that precisely regulates the information interpreted by the cells. Their work was published in Cell Report.30/07/2021
Scientific events
All scientific events
20 Apr
2023
Seminar
11h-12h
Acute and chronic endothelial cell responses modulate radiation therapy efficacy.
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25 Oct
2022
Seminar
10h-12h
"Role of innate-immune response and micro-environment on regenerative potential of salivary glands after photon and proton irradiation."