Presentation
Activity
The Institut Curie Mass Spectrometry and Proteomics facility (LSMP) was established in 2001 to answer a request in proteomics. This service consists of personnel with specialized know-how and expertise in the proteomics field as well as state-of-the-art proteomics equipment (MS, LC, softwares, etc..).
New collaborators are met to discuss the most appropriate way forward in their project. Altogether, we design the experiment so as to answer their questions. Some biological and biomedical questions will apply existing technologies. Others are technically more challenging and require the development of new techniques, reagents or software in order to solve pressing problems.
Aims
The LSMP facility aims to provide researchers with technical services enabling them to analyze proteins (identification of proteins, comparison of proteomes, analysis of post-translational modifications, identification of partners interacting with the protein of interest etc.) by mass spectrometry. One of the most promising approaches is combining qualitative and quantitative analysis in a single analytical run (adapted to research samples, which means high sensitivity and low-level quantitation). The goal is to provide our collaborators with scientific hypotheses more quickly and to functionally validate our quantified candidates.
Networking
The LSMP facility is an “Ile-de-France Proteomics facility” for cancer research labeled IBiSA, which is part of the “ Proteomics @ PSL Research University ” Montagne Sainte Geneviève Proteomic Facility. The LSMP is a founding member of Paris proteomics platforms network, is associated to the French Society for electrophoresis and proteomic analysis and to the French Society of Mass Spectrometry part of EuPA and HUPO.
Manager and Team
The LSMP facility is managed by Damarys Loew and has a team specialized in the field of 1) Mass spectrometry and proteomics 2) Biology and 3) Bioinformatics
- Dr Damarys Loew, mass spectrometry specialist and facility manager contact: Tél. : +33 (0)1 56 24 65 22 (spectro@curie.fr)
- Bérangère Lombard, MS engineer
- Florent Dingli, Proteomic engineer
- Vanessa MASSON : bio/MS engineer
- Léonie DEC : MS engineer
- Michael RICHARD : Biostatician
- Damien MACLARD : bioinformatics engineer
- Henri GUILHON : bioinformatics engineer
