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CCR5 adopts three homodimeric conformations that control cell surface delivery

8 May 2018Science Signaling

DOI : 10.1126/scisignal.aal2869

Authors

Jun Jin, Fanny Momboisse, Gaelle Boncompain, Florian Koensgen, Zhicheng Zhou, Nelia Cordeiro, Fernando Arenzana-Seisdedos, Franck Perez, Bernard Lagane, Esther Kellenberger, Anne Brelot

Abstract

Distinct dimeric conformations of the HIV-1 co-receptor CCR5 govern its appearance at the cell surface.

Members

FRANCK PEREZ

Directeur de recherche CNRS