Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions

Nom de la revue
Lab on a Chip
Marine Verhulsel, Anthony Simon, Moencopi Bernheim-Dennery, Venkata Ram Gannavarapu, Lauriane Gérémie, Davide Ferraro, Denis Krndija, Laurence Talini, Jean-Louis Viovy, Danijela Matic Vignjevic, Stéphanie Descroix

We report on a new gut on chip combining the co-culture of primary epithelial and stromal cells in 3D biomimetic scaffold. Proper segregation of dividing and differentiated cells along the crypt-villus axis was achieved in these unique conditions.