PhenDV, a turn-off fluorescent quadruplex DNA probe for improving the sensitivity of drug screening assays

Nom de la revue
Organic & Biomolecular Chemistry
Claire Beauvineau, Corinne Guetta, Marie-Paule Teulade-Fichou, Florence Mahuteau-Betzer

PhenDV is a light-up probe for G4-fluorescent intercalator displacement. This potent G4-DNA binder discriminates between medium and high-affinity ligands.