Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines

Science Advances
K. Hennig, I. Wang, P. Moreau, L. Valon, S. DeBeco, M. Coppey, Y. A. Miroshnikova, C. Albiges-Rizo, C. Favard, R. Voituriez, M. Balland
DOI
10.1126/sciadv.aau5670
Abstract

Cell motility can be initiated without prior cytoskeleton polarity by the stochastic stick-slip dynamics of cell adhesions.

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