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21 result(s)

2025Multiple oestradiol functions inhibit ferroptosis and acute kidney injuryNature
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2025Activation of lysosomal iron triggers ferroptosis in cancerNature
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2025Metal Ion Signaling in BiomedicineChemical Reviews
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2024Ageing of stem cells reduces their capacity to form tumoursNature
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2023The chemistry of next-generation sequencingNature Biotechnology
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2023A druggable copper-signalling pathway that drives inflammationNature
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2023Copper catalyses changes in cell stateNature
2022Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell DeathCancer Discovery
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2022Persister cancer cells: Iron addiction and vulnerability to ferroptosisMolecular Cell
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2020CD44 regulates epigenetic plasticity by mediating iron endocytosisNature Chemistry
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2018Visualizing biologically active small molecules in cells using click chemistryNature Reviews Chemistry
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2017Salinomycin kills cancer stem cells by sequestering iron in lysosomesNature Chemistry
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2017Click chemistry enables preclinical evaluation of targeted epigenetic therapiesScience
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2015Synthesis of marmycin A and investigation into its cellular activityNature Chemistry
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2014Unravelling the genomic targets of small molecules using high-throughput sequencingNature Reviews Genetics
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2014Chemical Inhibition of NAT10 Corrects Defects of Laminopathic CellsScience
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2012Selective RNA Versus DNA G‐Quadruplex Targeting by In Situ Click ChemistryAngewandte Chemie International Edition
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2012Small-molecule–induced DNA damage identifies alternative DNA structures in human genesNature Chemical Biology
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2011The transcription factor FOXM1 is a cellular target of the natural product thiostreptonNature Chemistry
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2010Small-molecule-mediated G-quadruplex isolation from human cellsNature Chemistry
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2008A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at TelomeresJournal of the American Chemical Society
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