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- The emerging immunogenomic landscape of uveal melanoma and therapeutic implications
The emerging immunogenomic landscape of uveal melanoma and therapeutic implications
21 March - 17h15 - 23h59
Centre de recherche - Paris
Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
12 rue Lhomond, Paris 5ème
Description
Uveal melanoma responds poorly to checkpoint inhibitor immunotherapy, which has been attributed to low mutation burden. Additionally, there is growing evidence that uveal melanomas actively suppress the tumor immune microenvironment via recurrent genetic aberrations such as BAP1 mutations. The role of recurrent genetic aberrations in immune evasion and potential therapeutic strategies will be discussed.
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The seminar will also be broadcasted online via Teams
Speakers
J. William Harbour
UT Southwestern Medical Center
Invited by
The Uveal Melanoma Medico-Scientific Program