Projects developed by the Genetic Epidemiology of Cancer Team (GEC) aim at characterizing genetic variants involved in familial cancers by considering effects of other genetic or non-genetic factors. In addition to variants involved in monogenic transmission, variants involved in polygenic modes of cancer inheritance are also studied, as well as their interactions with lifestyle and environmental exposures. Results from this research will in fine allow to improve risk prediction models and therefore to more precisely estimate tumor risks, which in turn will help elaborating personalized screening, follow up and new prevention strategies.
Genetic Epidemiology of Cancer
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