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Clinical trials - page 6

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195 result(s)

  • Eye tumors / Uveal melanoma
    Paris
    SALOME / IC 2019-13
    Follow-up of patients with uveal melanoma adapted to the risk of relapse.

    SOPHIE PIPERNO-NEUMANN

  • Cancer de l'ovaire
    Paris, Saint-Cloud
    SALVOVAR
    A pragmatic randomized phase III trial to assess the utility of adjusting;chemotherapy dose & dosing schedule with the SALVage weekly dose-dense;regimen in patients with poor prognostic OVARian cancers based on the tumor;unfavorable primary chemosensitivity and incomplete debulking surgery.

    CLEMENT BONNET

  • Paris, Saint-Cloud
    SCANDARE (IC 2016-03)
    Prospective biobanking study in ovarian, breast and head and neck cancer patients aiming at better understand the link between the molecular alterations of the tumor itself, its microenvironment and immune response.

    EDITH BORCOMAN

  • Saint-Cloud
    SERENA-4
    SERENA-4: A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) Plus Palbociclib Versus Anastrozole Plus Palbociclib for the Treatment of Patients With Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

    FRANCOIS-CLEMENT BIDARD

  • Saint-Cloud
    START
    A Randomized Phase 2 Study in Patients With Triple-negative Androgen Receptor Positive Locally Recurrent (Unresectable) or Metastatic Breast Cancer Treated With Darolutamide or Capecitabine

    FLORENCE LEREBOURS

  • Saint-Cloud
    STERIMGLI
    A Phase I/II Multicenter Trial Evaluating the Association of Hypofractionated Stereotactic Radiation Therapy and the Anti-Programmed Death-ligand 1 (PD-L1) Durvalumab (Medi4736) for Patients With Recurrent Glioblastoma (STERIMGLI).

  • Sarcomas
    Paris
    STRASS 2 - ETUDE 1809-STBSG
    A randomized phase III study of neoadjuvant chemotherapy;followed by surgery versus surgery alone for patients with;High Risk RetroPeritoneal Sarcoma (STRASS 2)

  • Saint-Cloud
    SUMMIT- PUMA-NER-0502
    An Open-label, Phase 2 Study of Neratinib in Patients With Solid Tumors With Somatic Human Epidermal Growth Factor Receptor (EGFR, HER2, HER3) Mutations or EGFR Gene Amplification.

    FRANCOIS-CLEMENT BIDARD

  • ENT/Head and Neck Cancers
    Paris, Saint-Cloud
    SURVEILLE HPV
    National, multicentre, open-label, randomised, phase II study evaluating HPV circulating DNA as biomarker to detect the recurrence, in order to improve post therapeutic surveillance of HPV-driven oropharyngeal cancers.

    JOEY MARTIN

  • Childhood and adolescent cancers
    Paris
    Selupass
    Post-Authorisation Safety Study of Paediatric Patients Initiating Selumetinib: A Multiple-Country Prospective Cohort Study

    ISABELLE AERTS GAJDOS

  • Lung cancer
    Paris
    TAS6417-201
    An Open-Label, Phase 2b, Global Multicenter Cohort Trial to;Assess the Safety and Efficacy of Zipalertinib in Patients;with Locally Advanced or Metastatic Non-Small Cell Lung;Cancer with Exon 20 Insertion and Uncommon/Single or;Compound Epidermal Growth Factor Receptor Mutations.

    NICOLAS GIRARD

  • Saint-Cloud
    TEDOPaM Prodige 63
    A randomized non-comparative phase II study of Maintenance therapy with OSE2101 plus FOLFIRI, or FOLFIRI after induction therapy with FOLFIRINOX in patients with locally advanced or metastatic Pancreatic ductal adenocarcinoma (TEDOPaM - D17-01 PRODIGE 63 Study).

  • ENT/Head and Neck Cancers
    Paris
    TG4050.02
    A randomized phase I trial in patients with newly-diagnosed, locoregionally advanced, HPV-negative, squamous cell carcinoma of the head and neck (SCCHN);evaluating a mutanome-directed immunotherapy;initiated at completion of primary treatment or at time of recurrence

    EDITH BORCOMAN

  • Breast cancer
    Paris
    TRANS ROSALEE
    A BIOMARKER-DIRECTED, TRANSLATIONAL STUDY OF HIGH-THROUGHPUT MOLECULAR PROFILING OF HR+/HER2- METASTATIC BREAST CANCER TREATED WITH ENDOCRINE THERAPY AND RIBOCICLIB.

    HELENE SALAUN

  • Lung cancer
    Paris
    TROPION LUNG 14
    A Phase III, Open-label, Randomised Study of Osimertinib;With or Without Datopotamab Deruxtecan (Dato-DXd), as;First-line Treatment in Participants With Epidermal Growth;Factor Receptor (EGFR) Mutation-positive, Locally Advanced;or Metastatic Non-small Cell Lung Cancer;(TROPION-Lung14)

    NICOLAS GIRARD

  • Paris
    TUMOSS
    Comparative Evaluation of Care Strategies on Dressing Change-induced Bleeding in Patients With Bleeding Malignant Wounds (TUMOSS)

  • Lung cancer
    Paris
    Telimet-01: M18-868
    A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin;(ABBV-399) Versus Docetaxel in Subjects with Previously Treated c-Met Overexpressing, EGFR Wildtype,;Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer.

    NICOLAS GIRARD

  • Breast cancer
    Paris, Saint-Cloud
    Treat ctDNA
    Elacestrant for Treating ER+/·HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) (TREAT ctDNA)

    FRANCOIS-CLEMENT BIDARD, ETIENNE BRAIN

  • Cancers gynécologiques
    Paris
    VS-6766-301 (RAMP 301)
    A Phase 3, Randomized, Open-Label Study of Combination Therapy with Avutometinib plus Defactinib Versus;InvestigatorÀs Choice of Treatment in Patients with Recurrent Low-Grade Serous Ovarian Cancer (LGSOC).

    MANUEL RODRIGUES

  • Saint-Cloud
    YO39523
    A Phase III, Multicenter, Randomized, Study of Atezolizumab Versus Placebo Administered in Combination With Paclitaxel, Carboplatin, and Bevacizumab to Patients With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

  • Childhood and adolescent cancers
    Paris
    eSMART
    European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors.

    ISABELLE AERTS GAJDOS

  • Colorectal cancer
    Saint-Cloud
    ADAGE - Prodige 34
    Randomised Phase III Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over.

  • Cancers gynécologiques
    Saint-Cloud
    AFTERGYN
    Optimize the Support of Patients in Pelvic Onco-gynecology Through Adapted Support Care in the Post-cancer Period. AFTERGYN Pilot Phase (AFTERGYN)

    DIANA BELLO ROUFAI

  • Saint-Cloud
    AIPAC
    AIPAC (Active Immunotherapy PAClitaxel): A Multicentre, Phase IIb, Randomised,Double Blind, Placebo-controlled Study in Hormone Receptor-positive Metastatic Breast Carcinoma Patients Receiving IMP321 (LAG-3Ig Fusion Protein) or Placebo as Adjunctive to a Standard Chemotherapy Treatment Regimen of Paclitaxel

    ETIENNE BRAIN

  • Breast cancer
    Paris, Saint-Cloud
    ALCINA-4 (IC 2020-11)
    Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4

    FRANCOIS-CLEMENT BIDARD

  • Paris, Saint-Cloud
    ALCYTA (IC 2020-12)
    Exploration of Adaptive Antitumoral Immune Cells Through Leukapheresis in Cancer Patients: ALCYTA

    NICOLAS GIRARD

  • Saint-Cloud
    ALPHABET
    Randomized phase III trial of the administration of trastuzumab + Alpelisib +/- fulvestrant versus trastuzumab + chemotherapy in patients with a PIK3CA mutation and previously treated for advanced HER2+ cancer

    FRANCOIS-CLEMENT BIDARD

  • Saint-Cloud
    AMEBICA - Prodige 38
    Randomised Phase II/III Study, Assessing the Safety and Efficacy of Modified Folfirinox Versus Gemcis in Locally Advanced, Unresectable and/or Metastatic Bile Duct Tumours.

  • Saint-Cloud
    AML LI-1
    A PROGRAMME OF DEVELOPMENT FOR OLDER PATIENTS WITH ACUTE MYELOID LEUKAEMIA AND HIGH RISK MYELODYSPLASTIC SYNDROME

    JACQUES VARGAFTIG

  • Saint-Cloud
    APACaP
    Multicenter, Randomized Study, Evaluation of Adapted Physical Activity Program in Patients With Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

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