The hosting structure
The Curie Institute Research Center
The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center
Institut Curie is a major player in cancer research and the fight against cancer. It consists of a hospital and a research center with more than 1000 employees with a strong international representation.
The objective of the Institut Curie Research Center is to develop fundamental research and use the knowledge generated to improve the diagnosis, prognosis and therapeutics of cancers within the continuum between fundamental research and innovation for the benefit of patients.
Job description
Laboratory
The "Repair, Radiation and Innovative Anti-Cancer Therapies" team (U1021/UMR3347/Université Paris-Saclay) specializes in developing new therapeutic strategies aimed at increasing the therapeutic index of radiotherapy. For over 10 years, the team has been actively involved in the development of FLASH radiotherapy (Favaudon et al., Science Translational Medicine, 2014), which reduces radiation-induced toxicities while maintaining anti-tumor efficacy comparable to that of conventional radiotherapy (known as the FLASH effect).
In close collaboration with the team's radiation oncologists and medical physicists, the project aims to conduct preclinical studies to validate the new FLASH-VHEE irradiator developed at Institut Curie, specially in the frame of the FRATHEA project [1].
Missions
· Design and implementation of in vivo experiments: conduct experimental protocols on animal models in compliance with ethical and regulatory standards; prepare and submit project authorization applications to the ethics committee.
· Animal care and monitoring: perform injections (IP, IV), sample collection, weighing, substance administration, anesthesia, and euthanasia; monitor clinical parameters and ensure animal welfare throughout the experiments.
· Biological analyses and sample processing: participate in the implementation of biological analyses (genotyping, histological sections, immunofluorescence), in collaboration with other team members.
· Data analysis: collect, organize, and analyze experimental data; document results and experimental reports in the electronic lab notebook.
Education and Skills
- MSc (or equivalent minimum) in Biology, Biotechnology, Life Sciences, or Physiology (Engineering degree or Master's level).
- Specific training in animal experimentation: Category B (user level) required; Category C (project designer level) preferred.
- Prior experience in in vivo experimentation required (long-term internship or similar position).
- Strong proficiency in animal handling techniques: injection (IP, IV), anesthesia, sample collection, euthanasia.
- Experience with biological analysis techniques: histology, flow cytometry, molecular biology (PCR, etc.).
- Ability to write experimental protocols and ethics authorization applications.
Required qualities
- Scientific rigor, strong observational skills, and critical thinking.
- Strong organizational skills and ability to work independently.
- Ability to work effectively in a multidisciplinary team (researchers, physicists, PhD students, clinicians).
- Good written and oral communication skills (French and/or English desired).
All our opportunities are open to people with disabilities.
Contract information
Type of contract: CDD
Starting date: Fall 2025
Duration: 12 months that can be extended
Working time: full time
Remuneration: according to the current grids
Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position: Orsay
Référence :
Contact
Plrase send your CV, letter of motivation and 2 references, to
Deadline for application : 15/11/2025
Date de parution de l'offre : 25/08/2025
Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity.
https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf