BENOIT SORRE

One striking property of embryonic tissues is their ability to self-organize in order to form well-defined patterns that prefigure the body plan. Combining the biophysics experimental toolbox (microfluidics, micro-fabrication,micro-patterning, advanced microscopy, modeling…) to Embryonic Stem Cells culture, we are designing in vitro model systems that allow us to study the minimal ingredients required to control the spatial organization of developping tissues and the relationship between an external cue (such as a morphogen gradient) and tissue organization.