Dynamic Control of Signaling and Gene Expression

Team

PASCAL HERSEN

Dynamic Control of Signaling and Gene Expression

We are an interdisciplinary team working at the frontier of physics and biology. We use microfabrication, microfluidics, fluorescence microscopy, synthetic biology and cell biology to dynamically play with cells, their signaling pathways and their gene regulatory networks.

Members

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ALVARO BANDERAS

Post-Doctoral Researcher

Pauline GEHAN

Post-Doctoral Researcher

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SIMON BARRAL

PhD Student

Key publications

2020

Autonomous and Assisted Control for Synthetic Microbiology
International Journal of Molecular Sciences

Alvaro Banderas, Matthias Le Bec, Céline Cordier, Pascal Hersen
(2020 03 Dec)
2020

Rational programming of history-dependent logic in cellular populations
Nature Communications

Ana Zúñiga, Sarah Guiziou, Pauline Mayonove, Zachary Ben Meriem, Miguel Camacho, Violaine Moreau, Luca Ciandrini, Pascal Hersen, Jerome Bonnet
(2020 01 Dec)
2019

A microfluidic device for inferring metabolic landscapes in yeast monolayer colonies
eLife

Zoran S Marinkovic, Clément Vulin, Mislav Acman, Xiaohu Song, Jean-Marc Di Meglio, Ariel B Lindner, Pascal Hersen
(2019 01 Jul)
2018

Identification of individual cells from z-stacks of bright-field microscopy images
Scientific Reports

Jean-Baptiste Lugagne, Srajan Jain, Pierre Ivanovitch, Zacchary Ben Meriem, Clément Vulin, Chiara Fracassi, Gregory Batt, Pascal Hersen
(2018 01 Dec)
2017

Balancing a genetic toggle switch by real-time feedback control and periodic forcing
Nature Communications

Jean-Baptiste Lugagne, Sebastián Sosa Carrillo, Melanie Kirch, Agnes Köhler, Gregory Batt, Pascal Hersen
(2017 01 Dec)

All publications

News

Le Dr Pascal Hersen, lauréat d’une ERC Proof of Concept Grant

Le 27 juillet dernier, le Dr Pascal Hersen, directeur de l'unité de recherche Physico-Chimie Curie et chef de l'équipe Contrôle dynamique de la signalisation et de l'expression génétique, a obtenu une bourse ERC Proof of Concept. Elle vient soutenir son projet "CyberSco.Py" qui vise à développer une solution de microscopie intelligente en temps réel.

02/08/2023

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Dynamic Control of Signaling and Gene Expression

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