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Unit
PASCAL HERSEN / MATHIEU COPPEY / ANTOINE COULON
Physics of Cells and Cancer (UMR168)

The goal of the unit is to uncover the role of physical laws in the architecture and functions of cellular systems. To this end, the teams follow cross-disciplinary approaches involving physics, chemistry and biology.

 

Key figures
150
physicists, chemists and biologists, including 35 researchers, 39 PhD students, 31 postdoctoral fellows and 28 technicians and engineers
13
Research teams labeled by prestigious funding agencies (ERC, ANR, H2020, FRM, ARC, La Ligue, etc ...)
4
state of the arts platforms in biochemistry and molecular biology, microfluidics, microfabrication, electron microscopy
Key publications
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News
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Scientific events
3 Jul
2024
Seminar
11h-23h
Molecular assembly and mechanics of single vimentin intermediate filaments
Intermediate filaments (IF) are involved in key cellular functions including polarization, migration, and protection against large deformations. These functions are related to their remarkable ability to extend without breaking, a capacity that should be determined by the molecular organization of subunits within filaments. However, this structure-mechanics relationship remains poorly understood a
24 Jun
2024
Seminar
14h-23h
Self-assembled active actomyosin gels spontaneously curve and wrinkle similar to biological cells and tissues
Living systems adopt a diversity of curved and highly dynamic shapes. These diverse morphologies appear on many length-scales, from cells to tissues and organismal scales. The common driving force for these dynamic shape changes are contractile stresses generated by myosin motors in the cell cytoskeleton, that converts chemical energy into mechanical work. A good understanding of how contractile s
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