CELINE CHAUVIN

Doctor

Recherche - Paris

Spécialités / domaines

Cell biology,

Molecular biology,

Cancer,

Screening,

Epigenetics,

Translational research

Functions within Institut Curie:

Research Engineer

Translational research in pediatric oncology (RTOP)
Unit : Cancer, Heterogeneity, Instability and Plasticity - CHIP (U830)

Department : Translational Research Department

Présentation

Céline Chauvin is an experienced research engineer in the Translational Research in Pediatric Oncology team.

After a PhD in fundamental research at Université Pierre et Marie Curie, she did a post-doc at Necker Hospital to study the implication of the mTOR pathway in the nutrient response. Then, she joined Curie Institute where she is now implicated in the identification of new therapeutic targets for rhabdoid tumors of the very young children. She is particularly interested in understanding the role of epigenetic regulators in rhabdoid tumors.

She is highly specialised in many domains like cell culture, gene expression and silencing (siRNA, CRISPR-Cas9 technologies), epigenetic (DNA methylation, histone modifications), drug treatment in vitro and in vivo, high-throughput screens, bioinformatic analyses of RNAseq and methylation profiling...

Publications

2021

Immune responses in genomically simple SWI/SNF–deficient cancers

Cancer

Amaury Leruste, Céline Chauvin, Celio Pouponnot, Franck Bourdeaut, Joshua J. Waterfall, Eliane Piaggio

(2021 15 Jan)

2019

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

Cancer Cell

Amaury Leruste, Jimena Tosello, Rodrigo Nalio Ramos, Arnault Tauziède-Espariat, Solène Brohard, Zhi-Yan Han, Kevin Beccaria, Mamy Andrianteranagna, Pamela Caudana, Jovan Nikolic, Céline Chauvin, Leticia Laura Niborski, Valeria Manriquez, Wilfrid Richer, Julien Masliah-Planchon, Sandrine Grossetête-Lalami, Mylene Bohec, Sonia Lameiras, Sylvain Baulande, Celio Pouponnot, Aurore Coulomb, Louise Galmiche, Didier Surdez, Nicolas Servant, Julie Helft, Christine Sedlik, Stéphanie Puget, Philippe Benaroch, Olivier Delattre, Joshua J. Waterfall, Eliane Piaggio, Franck Bourdeaut

(2019 01 Dec)

2017

High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors

Cell Reports

Céline Chauvin, Amaury Leruste, Arnault Tauziede-Espariat, Mamy Andrianteranagna, Didier Surdez, Aurianne Lescure, Zhi-Yan Han, Elodie Anthony, Wilfrid Richer, Sylvain Baulande, Mylène Bohec, Sakina Zaidi, Marie-Ming Aynaud, Laetitia Maillot, Julien Masliah-Planchon, Stefano Cairo, Sergio Roman-Roman, Olivier Delattre, Elaine Del Nery, Franck Bourdeaut

(2017 01 Nov)

2016

The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation

Nature Communications

Zhi-Yan Han, Wilfrid Richer, Paul Fréneaux, Céline Chauvin, Carlo Lucchesi, Delphine Guillemot, Camille Grison, Delphine Lequin, Gaelle Pierron, Julien Masliah-Planchon, André Nicolas, Dominique Ranchère-Vince, Pascale Varlet, Stéphanie Puget, Isabelle Janoueix-Lerosey, Olivier Ayrault, Didier Surdez, Olivier Delattre, Franck Bourdeaut

(2016 01 Apr)