Department
Translational Research Department
Thematic areas of research:
Image
To top
Department
SERGIO ROMAN ROMAN
Translational Research Department
Since 2003, Institut Curie has structured a « Translational Research Department » with the goal of promoting and facilitating this research which has the objective of transferring discoveries at the bench to the bedside of patients and vice verse in the form of diagnostic or therapeutic applications
Teams
Key figures
>100
department members in 2023
20
PhD Students in 2023
10
publications with an IF of >20 in 2023
Key publications
All publications
-
Integrated High-Throughput Screening and Large-Scale Isobolographic Analysis to Accelerate the Discovery of Radiosensitizers With Greater Selectivity for Cancer CellsInternational Journal of Radiation Oncology*Biology*Physics
-
-
Therapeutic Advantage of Targeting PRMT5 in Combination with Chemotherapies or EGFR/HER2 Inhibitors in Triple-Negative Breast CancersBreast Cancer: Targets and Therapy
-
-
-
-
-
Proton FLASH Radiation Therapy and Immune Infiltration: Evaluation in an Orthotopic Glioma Rat ModelInternational Journal of Radiation Oncology*Biology*Physics
-
-
Multi-modal quantification of pathway activity with MAYANature Communications
-
News
All news
-
World Triple Negative Breast Cancer Day: innovation to cure more womenWorld Triple Negative Breast Cancer Day, held on March 3rd, is a reminder that triple-negative breast cancers remain the most difficult to treat, and that only innovation and dynamic research can bring hope of curing more patients.01/03/2024 -
Aggressive uveal melanoma: new mechanisms revealedIn a study published in Cell Report on September 13, the CurieCoreTech Genomics Platform headed by Dr. David Gentien, the Integrative Functional Genomics of Cancer team (Inserm U830) led by Dr. Joshua Waterfall and the Translational Research Department headed by Dr. Sergio Roman Roman, used a wide variety of tests at the genome level to achieve three key results for understanding aggressive uveal melanoma.09/11/2023 -
Response to chemotherapy: finally a biomarker for triple negative breast cancerIn triple negative breast cancer, how do we select those patients who will respond to chemotherapy with platinum salts? In Nature Communications, a team from Institut Curie makes an interesting proposal: to use the homologous recombination defect as a biomarker.25/04/2023 -
Institut Curie certified as Integrated cancer research site for the third timeFollowing a call for applications launched in April 2022, Institut Curie had its integrated cancer research site project certified by France’s Institut national du cancer (Inca). Its goal is to better understand tumor recurrences in order to better prevent, detect and treat them.20/02/2023 -
L'Institut Curie au congrès de l'EACR 2022L’Institut Curie participe au rendez-vous annuel européen de la recherche et de l'innovation en oncologie, le congrès de l’European Association for Cancer Research, qui se tient du 20 au 23 juin à Séville en Espagne. Pour cette édition, Fatima Mechta-Grigoriou, directrice de recherche Inserm à la tête de l’équipe Stress et cancer, et Elisabetta Marangoni, chercheuse au sein du département de recherche translationnelle, y partagent leur expertise et récents travaux prometteurs dans la lutte contre le cancer.21/06/2022 -
Céline Vallot, médaille de l'innovation 2022 du CNRSLa médaille de l’innovation 2022 du CNRS a été remise le 16 juin 2022 par Sylvie Retailleau, ministre de l'Enseignement supérieur et de la Recherche, et Antoine Petit, président-directeur général du CNRS à Céline Vallot, biologiste et cheffe d’équipe au Centre de recherche de l’Institut Curie.16/06/2022
Scientific events
All scientific events
28 Feb
2024
Institutional seminar "Mayent - Rothschild"
13h-23h
Spliceosome Mutations in Myeloid Malignancy
The primary goal of Dan Larson's laboratory is to understand gene expression in eukaryotic cells, starting from the mechanistic behavior of individual macromolecules and proceeding to their regulation in cells and tissue.
The laboratory utilizes a battery of biophysical, molecular and genomic approaches, including single-molecule microscopy, RNA visualization in fixed and living cells, comput
The laboratory utilizes a battery of biophysical, molecular and genomic approaches, including single-molecule microscopy, RNA visualization in fixed and living cells, comput
6 Jun
2023
Conference
14h-23h
ChatGPT for scientific writing
Paul Gougis from the RT2 group will be conducting a presentation on the topic of chatGPT for scientific writing on Tuesday, June 6th at 14:00.
During the presentation, he will address practical aspects of utilizing chatGPT for medical writing, as well as some broader considerations.
The session will be conducted in English and will be recorded for future reference.
During the presentation, he will address practical aspects of utilizing chatGPT for medical writing, as well as some broader considerations.
The session will be conducted in English and will be recorded for future reference.
30 May
2023
31 May
2023
Conferences
13h-17h
Institut Curie Optical Genome Mapping (OGM) Meeting
Join us for our Institut Curie Optical Genome Mapping meeting in Paris on Tuesday and Wednesday, May 30-31, 2023 at Institut Curie. During this unique event, optical genome mapping (OGM) users and those who are OGM-curious will have an opportunity to learn and network with OGM pioneers as they present the impact that visualization of structural variation, through OGM, has had on their research for