FLAVIA BERNARDI

Doctor
Recherche - Orsay
Spécialités / domaines
Bioinformatique,
Biologie,
Biologie cellulaire,
Biologie moléculaire,
Cancer,
Signalisation
Functions within Institut Curie:
  • Post-Doctoral Researcher
    Signaling in Development and Brain Tumours
    Unit : Signaling, radiobiology and cancer (UMR3347 / U1021)
Présentation

Flavia is from Rome, and earned her Ph.D. in Molecular Medicine from the University of Rome. Her thesis project focused on ubiquitylation processes underlying the regulation of the Hedgehog pathway. After being awarded the international mobility grant from the French National Cancer Institute, she joined the laboratory in 2020 as a postdoctoral associate. Her work aims at characterizing enzymes of ubiquitination and deubiquitination implicated into medulloblastoma tumorigenesis. In parallel, she is also interested in pediatric brain tumor modeling through multi-omics data integration methods and proteomic-based approaches.

Publications
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Nature Communications
Francesca Bufalieri, Paola Infante, Flavia Bernardi, Miriam Caimano, Paolo Romania, Marta Moretti, Ludovica Lospinoso Severini, Julie Talbot, Ombretta Melaiu, Mirella Tanori, Laura Di Magno, Diana Bellavia, Carlo Capalbo, Stéphanie Puget, Enrico De Smaele, Gianluca Canettieri, Daniele Guardavaccaro, Luca Busino, Angelo Peschiaroli, Simonetta Pazzaglia, Giuseppe Giannini, Gerry Melino, Franco Locatelli, Alberto Gulino, Olivier Ayrault, Doriana Fruci, Lucia Di Marcotullio