MAGDA MAGIERA

Research interests

My main research interest is the role of the regulation of the microtubule cytoskeleton by posttranslational modifications. I focus mostly on tubulin polyglutamylation, the modification mostly enriched in neurons, and its impact on the regulation of neuronal function and in neurodegeneration. I have developed a number of murine models of polyglutamylation and analysed them at the organism and cellular levels. I also contribute to investigating the role of posttranslational modifications of tubulin in in vitro approaches.

Professional experience

• Oct 2020: CNRS permanent researcher (CRCN), Institut Curie, Orsay, France
• Oct 2008 – Oct 2020: non-permanent researcher with Carsten Janke, CRBM-CNRS, Montpellier, Institut Curie, Orsay, France, “Role of tubulin polyglutamylation in neurodegeneration.”
• Oct 2006 – Sept 2008: Post-doc with Solange Desagher, IGMM-CNRS, Montpellier, France, “Role of the anti-apoptotic protein, Mcl-1 in neuronal apoptosis.”
• Feb 2002 –Sept 2006: PhD with Etienne Schwob, IGMM-CNRS, Montpellier, France, “Checkpoint surveillance of the unperturbed DNA replication.”
• May 2001 – Jan 2002: Master project and Research Assistant with Miles D. Houslay, Institute of Biomedical and Life Sciences, University of Glasgow, UK, “Mechanism of action of PDE4, the multienzyme cAMP-specific phosphodiesterase family.”

Grants and prize

• AFM-Telethon, 2021-2023
• PSL-Biogen, 2020-2023
• Tom Wahlig Stiftung, 2020-2021
• Association France Alzheimer, 2020-2021
• Association Strümpell Lorrain - France, 2020-21
• Fondation Vaincre Alzheimer Pilot Award, 2017-2018

        Forcheurs Jean-Marie Lehn 2019 prize

Education

• HDR (Habilitation à Diriger les Recherches), Paris Sud-Paris Saclay, France, October 2019
• PhD of Université Montpellier II, France, September 2006
• Master in Molecular Biology, Jagiellonian University, Kraków, Poland, April 2001