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MARC-HENRI STERN

Doctor,
Directeur de recherche
Recherche - Paris
Spécialités / domaines
Bioinformatics,
Integrative tumor biology, immunology and environment,
Cancer,
Gynécologie,
Genomics,
Genetics,
Ophtalmologie
Functions within Institut Curie:
Présentation

Marc-Henri Stern received his doctorate in medicine and his PhD in Sciences (immunology) from the universities of Paris. After his postdoctoral training at N.C.I. (USA), he began his research team at Saint Louis Hospital, Paris, on leukemogenesis and DNA repair defects.

He joined the Curie Institute in 2000, setting up his team in the Inserm unit U830 unit led by Dr. Olivier Delattre, maintaining a medical activity within the Oncogenetics unit led by Prof. Dominique Stoppa-Lyonnet. His team is dedicated to unravel the genetic factors of tumor predisposition and of oncogenesis in adult tumors, including breast and ovarian carcinomas and uveal melanoma, ranging from fundamental and translational research to diagnosis.

Publications
Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma
Cell Reports
David Gentien, Elnaz Saberi-Ansari, Nicolas Servant, Ariane Jolly, Pierre de la Grange, Fariba Némati, Géraldine Liot, Simon Saule, Aurélie Teissandier, Deborah Bourc’his, Elodie Girard, Jennifer Wong, Julien Masliah-Planchon, Erkan Narmanli, Yuanlong Liu, Emma Torun, Rebecca Goulancourt, Manuel Rodrigues, Laure Villoing Gaudé, Cécile Reyes, Matéo Bazire, Thomas Chenegros, Emilie Henry, Audrey Rapinat, Mylene Bohec, Sylvain Baulande, Radhia M’kacher, Eric Jeandidier, André Nicolas, Giovanni Ciriello, Raphael Margueron, Didier Decaudin, Nathalie Cassoux, Sophie Piperno-Neumann, Marc-Henri Stern, Johan Harmen Gibcus, Job Dekker, Edith Heard, Sergio Roman-Roman, Joshua J. Waterfall
Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers
Nature Communications
Petra ter Brugge, Sarah C. Moser, Ivan Bièche, Petra Kristel, Sabrina Ibadioune, Alexandre Eeckhoutte, Roebi de Bruijn, Eline van der Burg, Catrin Lutz, Stefano Annunziato, Julian de Ruiter, Julien Masliah Planchon, Sophie Vacher, Laura Courtois, Rania El-Botty, Ahmed Dahmani, Elodie Montaudon, Ludivine Morisset, Laura Sourd, Léa Huguet, Heloise Derrien, Fariba Nemati, Sophie Chateau-Joubert, Thibaut Larcher, Anne Salomon, Didier Decaudin, Fabien Reyal, Florence Coussy, Tatiana Popova, Jelle Wesseling, Marc-Henri Stern, Jos Jonkers, Elisabetta Marangoni
Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer
Science Immunology
Antonela Merlotti, Benjamin Sadacca, Yago A. Arribas, Mercia Ngoma, Marianne Burbage, Christel Goudot, Alexandre Houy, Ares Rocañín-Arjó, Ana Lalanne, Agathe Seguin-Givelet, Marine Lefevre, Sandrine Heurtebise-Chrétien, Blandine Baudon, Giacomo Oliveira, Damarys Loew, Montserrat Carrascal, Catherine J. Wu, Olivier Lantz, Marc-Henri Stern, Nicolas Girard, Joshua J. Waterfall, Sebastian Amigorena
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements
Science Immunology
Marianne Burbage, Ares Rocañín-Arjó, Blandine Baudon, Yago A. Arribas, Antonela Merlotti, Derek C. Rookhuizen, Sandrine Heurtebise-Chrétien, Mengliang Ye, Alexandre Houy, Nina Burgdorf, Guadalupe Suarez, Marine Gros, Benjamin Sadacca, Montserrat Carrascal, Andrea Garmilla, Mylène Bohec, Sylvain Baulande, Bérangère Lombard, Damarys Loew, Joshua J. Waterfall, Marc-Henri Stern, Christel Goudot, Sebastian Amigorena
Microsatellite instability detection in breast cancer using drop-off droplet digital PCR
Oncogene
Khadidja Zeyneb Klouch, Marc-Henri Stern, Olfa Trabelsi-Grati, Nicolas Kiavue, Luc Cabel, Amanda Bortolini Silveira, Caroline Hego, Aurore Rampanou, Tatiana Popova, Guillaume Bataillon, Sarah Nasr, Charlotte Proudhon, Marc Michel, Victor Renault, Julien Masliah Planchon, Anne Vincent-Salomon, Jean-Yves Pierga, Ivan Bieche, Shufang Renault, François-Clément Bidard
Functional characterization of 5p15.33 risk locus in uveal melanoma reveals rs452384 as a functional variant and NKX2.4 as an allele-specific interactor
The American Journal of Human Genetics
Anne-Céline Derrien, Alexandre Houy, Olivier Ganier, Florent Dingli, Massih Ningarhari, Lenha Mobuchon, María Isabel Espejo Díaz, Damarys Loew, Nathalie Cassoux, Olivier Cussenot, Géraldine Cancel-Tassin, Raphael Margueron, Josselin Noirel, Jessica Zucman-Rossi, Manuel Rodrigues, Marc-Henri Stern
A catalog of numerical centrosome defects in epithelial ovarian cancers
EMBO Molecular Medicine
Jean‐Philippe Morretton, Anthony Simon, Aurélie Herbette, Jorge Barbazan, Carlos Pérez‐González, Camille Cosson, Bassirou Mboup, Aurélien Latouche, Tatiana Popova, Yann Kieffer, Anne‐Sophie Macé, Pierre Gestraud, Guillaume Bataillon, Véronique Becette, Didier Meseure, André Nicolas, Odette Mariani, Anne Vincent‐Salomon, Marc‐Henri Stern, Fatima Mechta‐Grigoriou, Sergio Roman Roman, Danijela Matic Vignjevic, Roman Rouzier, Xavier Sastre‐Garau, Oumou Goundiam, Renata Basto