PATRICIA BASSEREAU

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Biosketch

Patricia Bassereau is CNRS Directrice de Recherche at the Institut Curie in Paris where she is the leader of the group "Membranes and cellular functions". She obtained a short PhD and a PhD in Soft Matter at the University of Montpellier where she started her carrier on the structure of self-assembled surfactant-based systems. She spent one year as a visiting scientist at the IBM Almaden Center (San Jose, USA) on thin polymer films. She moved to the Institut Curie in 1993 to work on questions related to "Physics of the cell". She develops a multidisciplinary approach, largely based on synthetic biology and biomimetic systems, as well as quantitative mechanical and microscopy methods to understand the role of biological membranes and of their organization in cellular functions such as intracellular trafficking, endo/exocytosis or adhesion. Additionally, she studies in vitro and in cellulo the mechanics and the generation of cellular protrusions. In parallel, she contributes to a more comprehensive physical description of biomembranes by studying the consequences of non-equilibrium transmembrane transport of ions on membrane mechanics ("active membranes"), the relation between membrane proteins' shape and their diffusion or their lateral distribution on membranes.

Education

Master: Solid State Physics (1983), PhD (1985), PhD (1990) HdR (Habilitation) (1999)

Positions

GDPC-Montpellier (1983-1991)

IBM Almaden (USA) (1992)

Physical Chemistry Curie-Paris (1993-Present)

Research themes

Past:Soft Condensed Matter (Surfactants in solution, polymers, membranes) Current: Physics for Biology, Physics of bio-membranes

Current research

Intracellular traffic, non-equilibrium membranes, proteins clustering and dynamics in membranes, cellular protrusions