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CurieCoreTech Recombinant Antibodies
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FRANCK PEREZ
CurieCoreTech Recombinant Antibodies
The group uses its own fully synthetic phage display library of humanized llama recombinant single domain antibody that can provide high affinity binders without animal immunization. The library contains 3.109 independent nanobodies.
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Selection and Use of Intracellular AntibodiesAntibody Engineering
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Whole-cell biopanning with a synthetic phage display library of nanobodies enabled the recovery of follicle-stimulating hormone receptor inhibitorsBiochemical and Biophysical Research Communications
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Resolving bundled microtubules using anti-tubulin nanobodiesNature Communications
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CATCHFIRE: An innovative tool to control the private lives of cells and view them via fluorescenceResearchers from Institut Curie, the CNRS, Sorbonne University and ENS-PSL have just developed an innovative molecular tool. Known as CATCHFIRE, it lets you not only control the closeness of two proteins, but also view their proximity. These multi-disciplinary efforts offer a number of applications for study of basic biological processes, but also in biomedicine, for genetic and metabolic diseases for example, or in the field of cell therapy for cancer treatment. These results are published on August 28, 2023, in Nature Methods.06/09/2023 -
Cancer du sein triple négatif : vers une nouvelle génération de thérapies jamais exploréesParticulièrement impliqué dans la recherche sur le cancer du sein triple négatif, l’Institut Curie mène différents projets pour améliorer les traitements des femmes atteintes de ce type de cancer agressif. Parmi eux, le projet d’envergure CASSIOPEIA.03/03/2022