Constitutive resistance to viral infection in human CD141 + dendritic cells

21 Jul, 2017

Science Immunology

Aymeric Silvin, Chun I Yu, Xavier Lahaye, Francesco Imperatore, Jean-Baptiste Brault, Sylvain Cardinaud, Christian Becker, Wing-Hong Kwan, Cécile Conrad, Mathieu Maurin, Christel Goudot, Santy Marques-Ladeira, Yuanyuan Wang, Virginia Pascual, Esperanza Anguiano, Randy A. Albrecht, Matteo Iannacone, Adolfo García-Sastre, Bruno Goud, Marc Dalod, Arnaud Moris, Miriam Merad, A. Karolina Palucka, Nicolas Manel

DOI

10.1126/sciimmunol.aai8071

Abstract

Specialized human dendritic cells that resist viral infection activate T cells by relying on bystander cells for antigen production. See the related Focus by Wong
et al
.