Team
Signaling and Neural Crest Development
Thematic areas of research:
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Team
ANNE HELENE MONSORO BURQ
Signaling and Neural Crest Development
Forming a functional organism from a few stem cells is the challenge facing every embryo. The growth and early regionalization of an embryo require the precise orchestration in time and space of not only gene activity, but also a variety of post-transcriptional regulations. Understanding how the genetic programs that regulate embryo development, and in particular cell migration and morphogenesis, are encoded and regulated is a current challenge in developmental biology.
Members
Past members
ALEKSANDR KOTOV
PhD Student
MANSOUR ALKOBTAWI
PhD Student
DARIA BARSUK
Project Manager
LAURA MEDINA
PhD Student
Network
Key publications
All publications
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AKT signaling displays multifaceted functions in neural crest developmentDevelopmental Biology
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News
All news
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Deciphering the genetic programs of stem cells to better understand cancersResearchers at Institut Curie have recently identified the genetic programs responsible for the development and diversification of a particular population of stem cells at the origin, among other things, of the peripheral nervous system. These results, published in PNAS on May 7, were obtained by the team of Prof. Anne-Hélène Monsoro-Burq, group leader of the Team Signaling and Neural Crest Development (CNRS UMR3347 / Inserm U1021 / Paris-Saclay University). These results will allow us to better understand the diversification of stem cell descendants, but also to identify mechanisms that can potentially be used in the clinic, particularly in metastatic development.12/07/2024
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FHL3: A Scaffold Protein, Architect of the Embryonic Nervous SystemThe various signals that orchestrate the first notes of the concerto that is the nervous system are part of a very complex score! Even so, researchers from Institut Curie, CNRS, Inserm, and Université Paris-Saclay* have managed to decipher the role played by FHL3, a modulator that precisely regulates the information interpreted by the cells. Their work was published in Cell Report.30/07/2021